Karlene A Cimprich Selected Research

Poly(ADP-ribose) Polymerase Inhibitors

1/2021

Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination-deficient cancer models.

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Karlene A Cimprich Research Topics

Disease

6	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2022 - 10/2006
5	Neoplasms (Cancer) 01/2021 - 01/2006
4	Genomic Instability 01/2022 - 07/2007
2	Ciliopathies 09/2015 - 08/2013
2	Hypersensitivity (Allergy) 10/2009 - 01/2006
1	Hypoxia (Hypoxemia) 01/2021
1	Carcinogenesis 01/2020
1	Renal Insufficiency (Renal Failure) 09/2015
1	Cysts 09/2015
1	Cockayne Syndrome (Syndrome, Cockayne) 12/2014
1	Polycystic Kidney Diseases (Polycystic Kidney Disease) 08/2013
1	Nervous System Diseases (Neurological Disorders) 07/2009
1	Fanconi Anemia (Fanconi's Anemia) 01/2006

Drug/Important Bio-Agent (IBA)

7	DNA (Deoxyribonucleic Acid)IBA 10/2017 - 01/2006
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2007
3	Phosphotransferases (Kinase)IBA 10/2017 - 07/2013
2	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2022 - 12/2014
1	Oxygen (Dioxygen)IBA 01/2021
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2021
1	Tirapazamine (SR 4233)IBA 01/2021
1	Cytotoxins (Cytolysins)IBA 01/2021
1	Bortezomib (Velcade)FDA Link 12/2016
1	RNA (Ribonucleic Acid)IBA 07/2014
1	pleiotrophin (HARP)IBA 10/2009
1	Small Interfering RNA (siRNA)IBA 07/2009
1	Protein Kinases (Protein Kinase)IBA 08/2008
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 10/2006
1	Mitomycin (Mitomycin-C)FDA LinkGeneric 01/2006

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 01/2021 - 01/2020
1	Therapeutics 01/2021